LRP1B (англ. LDL receptor related protein 1B) – білок, який кодується однойменним геном, розташованим у людей на короткому плечі 2-ї хромосоми. Довжина поліпептидного ланцюга білка становить 4 599 амінокислот, а молекулярна маса — 515 498.
LRP1B | |||||||||||||||||
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Ідентифікатори | |||||||||||||||||
Символи | LRP1B, LRP-DIT, LRPDIT, LDL receptor related protein 1B, LRP-1B | ||||||||||||||||
Зовнішні ІД | OMIM: 608766 MGI: 2151136 HomoloGene: 56810 GeneCards: LRP1B | ||||||||||||||||
Пов'язані генетичні захворювання | |||||||||||||||||
періодонтит, рак простати, еректильна дисфункція | |||||||||||||||||
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Шаблон експресії | |||||||||||||||||
Більше даних | |||||||||||||||||
Ортологи | |||||||||||||||||
Види | Людина | Миша | |||||||||||||||
Entrez |
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Ensembl |
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UniProt |
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RefSeq (мРНК) |
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RefSeq (білок) |
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Локус (UCSC) | Хр. 2: 140.23 – 142.13 Mb | Хр. 2: 40.49 – 42.54 Mb | |||||||||||||||
PubMed search | |||||||||||||||||
Вікідані | |||||||||||||||||
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10 | 20 | 30 | 40 | 50 | ||||
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MSEFLLALLT | LSGLLPIARV | LTVGADRDQQ | LCDPGEFLCH | DHVTCVSQSW | ||||
LCDGDPDCPD | DSDESLDTCP | EEVEIKCPLN | HIACLGTNKC | VHLSQLCNGV | ||||
LDCPDGYDEG | VHCQELLSNC | QQLNCQYKCT | MVRNSTRCYC | EDGFEITEDG | ||||
RSCKDQDECA | VYGTCSQTCR | NTHGSYTCSC | VEGYLMQPDN | RSCKAKIEPT | ||||
DRPPILLIAN | FETIEVFYLN | GSKMATLSSV | NGNEIHTLDF | IYNEDMICWI | ||||
ESRESSNQLK | CIQITKAGGL | TDEWTINILQ | SFHNVQQMAI | DWLTRNLYFV | ||||
DHVGDRIFVC | NSNGSVCVTL | IDLELHNPKA | IAVDPIAGKL | FFTDYGNVAK | ||||
VERCDMDGMN | RTRIIDSKTE | QPAALALDLV | NKLVYWVDLY | LDYVGVVDYQ | ||||
GKNRHTVIQG | RQVRHLYGIT | VFEDYLYATN | SDNYNIVRIN | RFNGTDIHSL | ||||
IKIENAWGIR | IYQKRTQPTV | RSHACEVDPY | GMPGGCSHIC | LLSSSYKTRT | ||||
CRCRTGFNLG | SDGRSCKRPK | NELFLFYGKG | RPGIVRGMDL | NTKIADEYMI | ||||
PIENLVNPRA | LDFHAETNYI | YFADTTSFLI | GRQKIDGTER | ETILKDDLDN | ||||
VEGIAVDWIG | NNLYWTNDGH | RKTINVARLE | KASQSRKTLL | EGEMSHPRGI | ||||
VVDPVNGWMY | WTDWEEDEID | DSVGRIEKAW | MDGFNRQIFV | TSKMLWPNGL | ||||
TLDFHTNTLY | WCDAYYDHIE | KVFLNGTHRK | IVYSGRELNH | PFGLSHHGNY | ||||
VFWTDYMNGS | IFQLDLITSE | VTLLRHERPP | LFGLQIYDPR | KQQGDNMCRV | ||||
NNGGCSTLCL | AIPGGRVCAC | ADNQLLDENG | TTCTFNPGEA | LPHICKAGEF | ||||
RCKNRHCIQA | RWKCDGDDDC | LDGSDEDSVN | CFNHSCPDDQ | FKCQNNRCIP | ||||
KRWLCDGAND | CGSNEDESNQ | TCTARTCQVD | QFSCGNGRCI | PRAWLCDRED | ||||
DCGDQTDEMA | SCEFPTCEPL | TQFVCKSGRC | ISSKWHCDSD | DDCGDGSDEV | ||||
GCVHSCFDNQ | FRCSSGRCIP | GHWACDGDND | CGDFSDEAQI | NCTKEEIHSP | ||||
AGCNGNEFQC | HPDGNCVPDL | WRCDGEKDCE | DGSDEKGCNG | TIRLCDHKTK | ||||
FSCWSTGRCI | NKAWVCDGDI | DCEDQSDEDD | CDSFLCGPPK | HPCANDTSVC | ||||
LQPEKLCNGK | KDCPDGSDEG | YLCDECSLNN | GGCSNHCSVV | PGRGIVCSCP | ||||
EGLQLNKDNK | TCEIVDYCSN | HLKCSQVCEQ | HKHTVKCSCY | EGWKLDVDGE | ||||
SCTSVDPFEA | FIIFSIRHEI | RRIDLHKRDY | SLLVPGLRNT | IALDFHFNQS | ||||
LLYWTDVVED | RIYRGKLSES | GGVSAIEVVV | EHGLATPEGL | TVDWIAGNIY | ||||
WIDSNLDQIE | VAKLDGSLRT | TLIAGAMEHP | RAIALDPRYG | ILFWTDWDAN | ||||
FPRIESASMS | GAGRKTIYKD | MKTGAWPNGL | TVDHFEKRIV | WTDARSDAIY | ||||
SALYDGTNMI | EIIRGHEYLS | HPFAVSLYGS | EVYWTDWRTN | TLSKANKWTG | ||||
QNVSVIQKTS | AQPFDLQIYH | PSRQPQAPNP | CAANDGKGPC | SHMCLINHNR | ||||
SAACACPHLM | KLSSDKKTCY | EMKKFLLYAR | RSEIRGVDID | NPYFNFITAF | ||||
TVPDIDDVTV | IDFDASEERL | YWTDIKTQTI | KRAFINGTGL | ETVISRDIQS | ||||
IRGLAVDWVS | RNLYWISSEF | DETQINVARL | DGSLKTSIIH | GIDKPQCLAA | ||||
HPVRGKLYWT | DGNTINMANM | DGSNSKILFQ | NQKEPVGLSI | DYVENKLYWI | ||||
SSGNGTINRC | NLDGGNLEVI | ESMKEELTKA | TALTIMDKKL | WWADQNLAQL | ||||
GTCSKRDGRN | PTILRNKTSG | VVHMKVYDKE | AQQGSNSCQL | NNGGCSQLCL | ||||
PTSETTRTCM | CTVGYYLQKN | RMSCQGIESF | LMYSVHEGIR | GIPLEPSDKM | ||||
DALMPISGTS | FAVGIDFHAE | NDTIYWTDMG | FNKISRAKRD | QTWKEDIITN | ||||
GLGRVEGIAV | DWIAGNIYWT | DHGFNLIEVA | RLNGSFRYVI | ISQGLDQPRS | ||||
IAVHPEKGLL | FWTEWGQMPC | IGKARLDGSE | KVVLVSMGIA | WPNGISIDYE | ||||
ENKLYWCDAR | TDKIERIDLE | TGGNREMVLS | GSNVDMFSVA | VFGAYIYWSD | ||||
RAHANGSVRR | GHKNDATETI | TMRTGLGVNL | KEVKIFNRVR | EKGTNVCARD | ||||
NGGCKQLCLY | RGNSRRTCAC | AHGYLAEDGV | TCLRHEGYLL | YSGRTILKSI | ||||
HLSDETNLNS | PIRPYENPRY | FKNVIALAFD | YNQRRKGTNR | IFYSDAHFGN | ||||
IQLIKDNWED | RQVIVENVGS | VEGLAYHRAW | DTLYWTSSTT | SSITRHTVDQ | ||||
TRPGAFDREA | VITMSEDDHP | HVLALDECQN | LMFWTNWNEQ | HPSIMRSTLT | ||||
GKNAQVVVST | DILTPNGLTI | DYRAEKLYFS | DGSLGKIERC | EYDGSQRHVI | ||||
VKSGPGTFLS | LAVYDNYIFW | SDWGRRAILR | SNKYTGGDTK | ILRSDIPHQP | ||||
MGIIAVANDT | NSCELSPCAL | LNGGCHDLCL | LTPNGRVNCS | CRGDRILLED | ||||
NRCVTKNSSC | NAYSEFECGN | GECIDYQLTC | DGIPHCKDKS | DEKLLYCENR | ||||
SCRRGFKPCY | NRRCIPHGKL | CDGENDCGDN | SDELDCKVST | CATVEFRCAD | ||||
GTCIPRSARC | NQNIDCADAS | DEKNCNNTDC | THFYKLGVKT | TGFIRCNSTS | ||||
LCVLPTWICD | GSNDCGDYSD | ELKCPVQNKH | KCEENYFSCP | SGRCILNTWI | ||||
CDGQKDCEDG | RDEFHCDSSC | SWNQFACSAQ | KCISKHWICD | GEDDCGDGLD | ||||
ESDSICGAIT | CAADMFSCQG | SRACVPRHWL | CDGERDCPDG | SDELSTAGCA | ||||
PNNTCDENAF | MCHNKVCIPK | QFVCDHDDDC | GDGSDESPQC | GYRQCGTEEF | ||||
SCADGRCLLN | TQWQCDGDFD | CPDHSDEAPL | NPKCKSAEQS | CNSSFFMCKN | ||||
GRCIPSGGLC | DNKDDCGDGS | DERNCHINEC | LSKKVSGCSQ | DCQDLPVSYK | ||||
CKCWPGFQLK | DDGKTCVDID | ECSSGFPCSQ | QCINTYGTYK | CLCTDGYEIQ | ||||
PDNPNGCKSL | SDEEPFLILA | DHHEIRKIST | DGSNYTLLKQ | GLNNVIAIDF | ||||
DYREEFIYWI | DSSRPNGSRI | NRMCLNGSDI | KVVHNTAVPN | ALAVDWIGKN | ||||
LYWSDTEKRI | IEVSKLNGLY | PTILVSKRLK | FPRDLSLDPQ | AGYLYWIDCC | ||||
EYPHIGRVGM | DGTNQSVVIE | TKISRPMALT | IDYVNRRLYW | ADENHIEFSN | ||||
MDGSHRHKVP | NQDIPGVIAL | TLFEDYIYWT | DGKTKSLSRA | HKTSGADRLS | ||||
LIYSWHAITD | IQVYHSYRQP | DVSKHLCMIN | NGGCSHLCLL | APGKTHTCAC | ||||
PTNFYLAADN | RTCLSNCTAS | QFRCKTDKCI | PFWWKCDTVD | DCGDGSDEPD | ||||
DCPEFRCQPG | RFQCGTGLCA | LPAFICDGEN | DCGDNSDELN | CDTHVCLSGQ | ||||
FKCTKNQKCI | PVNLRCNGQD | DCGDEEDERD | CPENSCSPDY | FQCKTTKHCI | ||||
SKLWVCDEDP | DCADASDEAN | CDKKTCGPHE | FQCKNNNCIP | DHWRCDSQND | ||||
CSDNSDEENC | KPQTCTLKDF | LCANGDCVSS | RFWCDGDFDC | ADGSDERNCE | ||||
TSCSKDQFRC | SNGQCIPAKW | KCDGHEDCKY | GEDEKSCEPA | SPTCSSREYI | ||||
CASDGCISAS | LKCNGEYDCA | DGSDEMDCVT | ECKEDQFRCK | NKAHCIPIRW | ||||
LCDGIHDCVD | GSDEENCERG | GNICRADEFL | CNNSLCKLHF | WVCDGEDDCG | ||||
DNSDEAPDMC | VKFLCPSTRP | HRCRNNRICL | QSEQMCNGID | ECGDNSDEDH | ||||
CGGKLTYKAR | PCKKDEFACS | NKKCIPMDLQ | CDRLDDCGDG | SDEQGCRIAP | ||||
TEYTCEDNVN | PCGDDAYCNQ | IKTSVFCRCK | PGFQRNMKNR | QCEDLNECLV | ||||
FGTCSHQCIN | VEGSYKCVCD | QNFQERNNTC | IAEGSEDQVL | YIANDTDILG | ||||
FIYPFNYSGD | HQQISHIEHN | SRITGMDVYY | QRDMIIWSTQ | FNPGGIFYKR | ||||
IHGREKRQAN | SGLICPEFKR | PRDIAVDWVA | GNIYWTDHSR | MHWFSYYTTH | ||||
WTSLRYSINV | GQLNGPNCTR | LLTNMAGEPY | AIAVNPKRGM | MYWTVVGDHS | ||||
HIEEAAMDGT | LRRILVQKNL | QRPTGLAVDY | FSERIYWADF | ELSIIGSVLY | ||||
DGSNSVVSVS | SKQGLLHPHR | IDIFEDYIYG | AGPKNGVFRV | QKFGHGSVEY | ||||
LALNIDKTKG | VLISHRYKQL | DLPNPCLDLA | CEFLCLLNPS | GATCVCPEGK | ||||
YLINGTCNDD | SLLDDSCKLT | CENGGRCILN | EKGDLRCHCW | PSYSGERCEV | ||||
NHCSNYCQNG | GTCVPSVLGR | PTCSCALGFT | GPNCGKTVCE | DFCQNGGTCI | ||||
VTAGNQPYCH | CQPEYTGDRC | QYYVCHHYCV | NSESCTIGDD | GSVECVCPTR | ||||
YEGPKCEVDK | CVRCHGGHCI | INKDSEDIFC | NCTNGKIASS | CQLCDGYCYN | ||||
GGTCQLDPET | NVPVCLCSTN | WSGTQCERPA | PKSSKSDHIS | TRSIAIIVPL | ||||
VLLVTLITTL | VIGLVLCKRK | RRTKTIRRQP | IINGGINVEI | GNPSYNMYEV | ||||
DHDHNDGGLL | DPGFMIDPTK | ARYIGGGPSA | FKLPHTAPPI | YLNSDLKGPL | ||||
TAGPTNYSNP | VYAKLYMDGQ | NCRNSLGSVD | ERKELLPKKI | EIGIRETVA |
Кодований геном білок за функціями належить до рецепторів, фосфопротеїнів. Задіяний у таких біологічних процесах як ендоцитоз, поліморфізм. Білок має сайт для зв'язування з іоном кальцію. Локалізований у мембрані.
Література
- Liu C.-X., Musco S., Lisitsina N.M., Yaklichkin S.Y., Lisitsyn N.A. (2000). Genomic organization of a new candidate tumor suppressor gene, LRP1B. Genomics. 69: 271—274. PMID 11031110 DOI:10.1006/geno.2000.6331
- Liu C.-X., Li Y., Obermoeller-McCormick L.M., Schwartz A.L., Bu G. (2001). The putative tumor suppressor LRP1B, a novel member of the low density lipoprotein (LDL) receptor family, exhibits both overlapping and distinct properties with the LDL receptor-related protein. J. Biol. Chem. 276: 28889—28896. PMID 11384978 DOI:10.1074/jbc.M102727200
Примітки
- Захворювання, генетично пов'язані з LRP1B переглянути/редагувати посилання на ВікіДаних.
- Human PubMed Reference:.
- Mouse PubMed Reference:.
- (англ.) . Архів оригіналу за 31 липня 2017. Процитовано 29 серпня 2017.
- (англ.) . Архів оригіналу за 31 липня 2017. Процитовано 29 серпня 2017.
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LRP1B angl LDL receptor related protein 1B bilok yakij koduyetsya odnojmennim genom roztashovanim u lyudej na korotkomu plechi 2 yi hromosomi Dovzhina polipeptidnogo lancyuga bilka stanovit 4 599 aminokislot a molekulyarna masa 515 498 LRP1BIdentifikatoriSimvoliLRP1B LRP DIT LRPDIT LDL receptor related protein 1B LRP 1BZovnishni ID OMIM 608766 MGI 2151136 HomoloGene 56810 GeneCards LRP1BPov yazani genetichni zahvoryuvannyaperiodontit rak prostati erektilna disfunkciya Ontologiya genaMolekulyarna funkciya calcium ion bindingKlitinna komponenta integral component of membrane receptor complex membranaBiologichnij proces protein transport endocitoz receptor oposeredkovanij endocitozDzherela Amigo QuickGOShablon ekspresiyiBilshe danihOrtologiVidi Lyudina MishaEntrez53353 94217Ensembl ENSG00000168702 ENSMUSG00000049252UniProt Q9NZR2 Q9JI18RefSeq mRNK NM 018557NM 053011RefSeq bilok NP 061027n dLokus UCSC Hr 2 140 23 142 13 MbHr 2 40 49 42 54 MbPubMed searchVikidaniDiv Red dlya lyudejDiv Red dlya mishej Poslidovnist aminokislot1020304050 MSEFLLALLTLSGLLPIARVLTVGADRDQQLCDPGEFLCHDHVTCVSQSW LCDGDPDCPDDSDESLDTCPEEVEIKCPLNHIACLGTNKCVHLSQLCNGV LDCPDGYDEGVHCQELLSNCQQLNCQYKCTMVRNSTRCYCEDGFEITEDG RSCKDQDECAVYGTCSQTCRNTHGSYTCSCVEGYLMQPDNRSCKAKIEPT DRPPILLIANFETIEVFYLNGSKMATLSSVNGNEIHTLDFIYNEDMICWI ESRESSNQLKCIQITKAGGLTDEWTINILQSFHNVQQMAIDWLTRNLYFV DHVGDRIFVCNSNGSVCVTLIDLELHNPKAIAVDPIAGKLFFTDYGNVAK VERCDMDGMNRTRIIDSKTEQPAALALDLVNKLVYWVDLYLDYVGVVDYQ GKNRHTVIQGRQVRHLYGITVFEDYLYATNSDNYNIVRINRFNGTDIHSL IKIENAWGIRIYQKRTQPTVRSHACEVDPYGMPGGCSHICLLSSSYKTRT CRCRTGFNLGSDGRSCKRPKNELFLFYGKGRPGIVRGMDLNTKIADEYMI PIENLVNPRALDFHAETNYIYFADTTSFLIGRQKIDGTERETILKDDLDN VEGIAVDWIGNNLYWTNDGHRKTINVARLEKASQSRKTLLEGEMSHPRGI VVDPVNGWMYWTDWEEDEIDDSVGRIEKAWMDGFNRQIFVTSKMLWPNGL TLDFHTNTLYWCDAYYDHIEKVFLNGTHRKIVYSGRELNHPFGLSHHGNY VFWTDYMNGSIFQLDLITSEVTLLRHERPPLFGLQIYDPRKQQGDNMCRV NNGGCSTLCLAIPGGRVCACADNQLLDENGTTCTFNPGEALPHICKAGEF RCKNRHCIQARWKCDGDDDCLDGSDEDSVNCFNHSCPDDQFKCQNNRCIP KRWLCDGANDCGSNEDESNQTCTARTCQVDQFSCGNGRCIPRAWLCDRED DCGDQTDEMASCEFPTCEPLTQFVCKSGRCISSKWHCDSDDDCGDGSDEV GCVHSCFDNQFRCSSGRCIPGHWACDGDNDCGDFSDEAQINCTKEEIHSP AGCNGNEFQCHPDGNCVPDLWRCDGEKDCEDGSDEKGCNGTIRLCDHKTK FSCWSTGRCINKAWVCDGDIDCEDQSDEDDCDSFLCGPPKHPCANDTSVC LQPEKLCNGKKDCPDGSDEGYLCDECSLNNGGCSNHCSVVPGRGIVCSCP EGLQLNKDNKTCEIVDYCSNHLKCSQVCEQHKHTVKCSCYEGWKLDVDGE SCTSVDPFEAFIIFSIRHEIRRIDLHKRDYSLLVPGLRNTIALDFHFNQS LLYWTDVVEDRIYRGKLSESGGVSAIEVVVEHGLATPEGLTVDWIAGNIY WIDSNLDQIEVAKLDGSLRTTLIAGAMEHPRAIALDPRYGILFWTDWDAN FPRIESASMSGAGRKTIYKDMKTGAWPNGLTVDHFEKRIVWTDARSDAIY SALYDGTNMIEIIRGHEYLSHPFAVSLYGSEVYWTDWRTNTLSKANKWTG QNVSVIQKTSAQPFDLQIYHPSRQPQAPNPCAANDGKGPCSHMCLINHNR SAACACPHLMKLSSDKKTCYEMKKFLLYARRSEIRGVDIDNPYFNFITAF TVPDIDDVTVIDFDASEERLYWTDIKTQTIKRAFINGTGLETVISRDIQS IRGLAVDWVSRNLYWISSEFDETQINVARLDGSLKTSIIHGIDKPQCLAA HPVRGKLYWTDGNTINMANMDGSNSKILFQNQKEPVGLSIDYVENKLYWI SSGNGTINRCNLDGGNLEVIESMKEELTKATALTIMDKKLWWADQNLAQL GTCSKRDGRNPTILRNKTSGVVHMKVYDKEAQQGSNSCQLNNGGCSQLCL PTSETTRTCMCTVGYYLQKNRMSCQGIESFLMYSVHEGIRGIPLEPSDKM DALMPISGTSFAVGIDFHAENDTIYWTDMGFNKISRAKRDQTWKEDIITN GLGRVEGIAVDWIAGNIYWTDHGFNLIEVARLNGSFRYVIISQGLDQPRS IAVHPEKGLLFWTEWGQMPCIGKARLDGSEKVVLVSMGIAWPNGISIDYE ENKLYWCDARTDKIERIDLETGGNREMVLSGSNVDMFSVAVFGAYIYWSD RAHANGSVRRGHKNDATETITMRTGLGVNLKEVKIFNRVREKGTNVCARD NGGCKQLCLYRGNSRRTCACAHGYLAEDGVTCLRHEGYLLYSGRTILKSI HLSDETNLNSPIRPYENPRYFKNVIALAFDYNQRRKGTNRIFYSDAHFGN IQLIKDNWEDRQVIVENVGSVEGLAYHRAWDTLYWTSSTTSSITRHTVDQ TRPGAFDREAVITMSEDDHPHVLALDECQNLMFWTNWNEQHPSIMRSTLT GKNAQVVVSTDILTPNGLTIDYRAEKLYFSDGSLGKIERCEYDGSQRHVI VKSGPGTFLSLAVYDNYIFWSDWGRRAILRSNKYTGGDTKILRSDIPHQP MGIIAVANDTNSCELSPCALLNGGCHDLCLLTPNGRVNCSCRGDRILLED NRCVTKNSSCNAYSEFECGNGECIDYQLTCDGIPHCKDKSDEKLLYCENR SCRRGFKPCYNRRCIPHGKLCDGENDCGDNSDELDCKVSTCATVEFRCAD GTCIPRSARCNQNIDCADASDEKNCNNTDCTHFYKLGVKTTGFIRCNSTS LCVLPTWICDGSNDCGDYSDELKCPVQNKHKCEENYFSCPSGRCILNTWI CDGQKDCEDGRDEFHCDSSCSWNQFACSAQKCISKHWICDGEDDCGDGLD ESDSICGAITCAADMFSCQGSRACVPRHWLCDGERDCPDGSDELSTAGCA PNNTCDENAFMCHNKVCIPKQFVCDHDDDCGDGSDESPQCGYRQCGTEEF SCADGRCLLNTQWQCDGDFDCPDHSDEAPLNPKCKSAEQSCNSSFFMCKN GRCIPSGGLCDNKDDCGDGSDERNCHINECLSKKVSGCSQDCQDLPVSYK CKCWPGFQLKDDGKTCVDIDECSSGFPCSQQCINTYGTYKCLCTDGYEIQ PDNPNGCKSLSDEEPFLILADHHEIRKISTDGSNYTLLKQGLNNVIAIDF DYREEFIYWIDSSRPNGSRINRMCLNGSDIKVVHNTAVPNALAVDWIGKN LYWSDTEKRIIEVSKLNGLYPTILVSKRLKFPRDLSLDPQAGYLYWIDCC EYPHIGRVGMDGTNQSVVIETKISRPMALTIDYVNRRLYWADENHIEFSN MDGSHRHKVPNQDIPGVIALTLFEDYIYWTDGKTKSLSRAHKTSGADRLS LIYSWHAITDIQVYHSYRQPDVSKHLCMINNGGCSHLCLLAPGKTHTCAC PTNFYLAADNRTCLSNCTASQFRCKTDKCIPFWWKCDTVDDCGDGSDEPD DCPEFRCQPGRFQCGTGLCALPAFICDGENDCGDNSDELNCDTHVCLSGQ FKCTKNQKCIPVNLRCNGQDDCGDEEDERDCPENSCSPDYFQCKTTKHCI SKLWVCDEDPDCADASDEANCDKKTCGPHEFQCKNNNCIPDHWRCDSQND CSDNSDEENCKPQTCTLKDFLCANGDCVSSRFWCDGDFDCADGSDERNCE TSCSKDQFRCSNGQCIPAKWKCDGHEDCKYGEDEKSCEPASPTCSSREYI CASDGCISASLKCNGEYDCADGSDEMDCVTECKEDQFRCKNKAHCIPIRW LCDGIHDCVDGSDEENCERGGNICRADEFLCNNSLCKLHFWVCDGEDDCG DNSDEAPDMCVKFLCPSTRPHRCRNNRICLQSEQMCNGIDECGDNSDEDH CGGKLTYKARPCKKDEFACSNKKCIPMDLQCDRLDDCGDGSDEQGCRIAP TEYTCEDNVNPCGDDAYCNQIKTSVFCRCKPGFQRNMKNRQCEDLNECLV FGTCSHQCINVEGSYKCVCDQNFQERNNTCIAEGSEDQVLYIANDTDILG FIYPFNYSGDHQQISHIEHNSRITGMDVYYQRDMIIWSTQFNPGGIFYKR IHGREKRQANSGLICPEFKRPRDIAVDWVAGNIYWTDHSRMHWFSYYTTH WTSLRYSINVGQLNGPNCTRLLTNMAGEPYAIAVNPKRGMMYWTVVGDHS HIEEAAMDGTLRRILVQKNLQRPTGLAVDYFSERIYWADFELSIIGSVLY DGSNSVVSVSSKQGLLHPHRIDIFEDYIYGAGPKNGVFRVQKFGHGSVEY LALNIDKTKGVLISHRYKQLDLPNPCLDLACEFLCLLNPSGATCVCPEGK YLINGTCNDDSLLDDSCKLTCENGGRCILNEKGDLRCHCWPSYSGERCEV NHCSNYCQNGGTCVPSVLGRPTCSCALGFTGPNCGKTVCEDFCQNGGTCI VTAGNQPYCHCQPEYTGDRCQYYVCHHYCVNSESCTIGDDGSVECVCPTR YEGPKCEVDKCVRCHGGHCIINKDSEDIFCNCTNGKIASSCQLCDGYCYN GGTCQLDPETNVPVCLCSTNWSGTQCERPAPKSSKSDHISTRSIAIIVPL VLLVTLITTLVIGLVLCKRKRRTKTIRRQPIINGGINVEIGNPSYNMYEV DHDHNDGGLLDPGFMIDPTKARYIGGGPSAFKLPHTAPPIYLNSDLKGPL TAGPTNYSNPVYAKLYMDGQNCRNSLGSVDERKELLPKKIEIGIRETVA A Alanin C Cisteyin D Asparaginova kislota E Glutaminova kislota F Fenilalanin G Glicin H Gistidin I Izolejcin K Lizin L Lejcin M Metionin N Asparagin P Prolin Q Glutamin R Arginin S Serin T Treonin V Valin W Triptofan Y Tirozin Kodovanij genom bilok za funkciyami nalezhit do receptoriv fosfoproteyiniv Zadiyanij u takih biologichnih procesah yak endocitoz polimorfizm Bilok maye sajt dlya zv yazuvannya z ionom kalciyu Lokalizovanij u membrani LiteraturaLiu C X Musco S Lisitsina N M Yaklichkin S Y Lisitsyn N A 2000 Genomic organization of a new candidate tumor suppressor gene LRP1B Genomics 69 271 274 PMID 11031110 DOI 10 1006 geno 2000 6331 Liu C X Li Y Obermoeller McCormick L M Schwartz A L Bu G 2001 The putative tumor suppressor LRP1B a novel member of the low density lipoprotein LDL receptor family exhibits both overlapping and distinct properties with the LDL receptor related protein J Biol Chem 276 28889 28896 PMID 11384978 DOI 10 1074 jbc M102727200PrimitkiZahvoryuvannya genetichno pov yazani z LRP1B pereglyanuti redaguvati posilannya na VikiDanih Human PubMed Reference Mouse PubMed Reference angl Arhiv originalu za 31 lipnya 2017 Procitovano 29 serpnya 2017 angl Arhiv originalu za 31 lipnya 2017 Procitovano 29 serpnya 2017 Div takozhHromosoma 2 Ce nezavershena stattya pro bilki Vi mozhete dopomogti proyektu vipravivshi abo dopisavshi yiyi