MUC5AC (англ. Mucin 5AC, oligomeric mucus/gel-forming) – білок, який кодується однойменним геном, розташованим у людей на короткому плечі 11-ї хромосоми. Довжина поліпептидного ланцюга білка становить 5 654 амінокислот, а молекулярна маса — 585 570.
MUC5AC | |||||||||||||||||
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Ідентифікатори | |||||||||||||||||
Символи | MUC5AC, MUC5, TBM, leB, mucin, mucin 5AC, oligomeric mucus/gel-forming | ||||||||||||||||
Зовнішні ІД | OMIM: 158373 MGI: 104697 HomoloGene: 137237 GeneCards: MUC5AC | ||||||||||||||||
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Ортологи | |||||||||||||||||
Види | Людина | Миша | |||||||||||||||
Entrez |
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Ensembl |
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UniProt |
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RefSeq (мРНК) |
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RefSeq (білок) |
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Локус (UCSC) | Хр. 11: 1.16 – 1.2 Mb | Хр. 7: 141.34 – 141.37 Mb | |||||||||||||||
PubMed search | |||||||||||||||||
Вікідані | |||||||||||||||||
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10 | 20 | 30 | 40 | 50 | ||||
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MSVGRRKLAL | LWALALALAC | TRHTGHAQDG | SSESSYKHHP | ALSPIARGPS | ||||
GVPLRGATVF | PSLRTIPVVR | ASNPAHNGRV | CSTWGSFHYK | TFDGDVFRFP | ||||
GLCNYVFSEH | CGAAYEDFNI | QLRRSQESAA | PTLSRVLMKV | DGVVIQLTKG | ||||
SVLVNGHPVL | LPFSQSGVLI | QQSSSYTKVE | ARLGLVLMWN | HDDSLLLELD | ||||
TKYANKTCGL | CGDFNGMPVV | SELLSHNTKL | TPMEFGNLQK | MDDPTDQCQD | ||||
PVPEPPRNCS | TGFGICEELL | HGQLFSGCVA | LVDVGSYLEA | CRQDLCFCED | ||||
TDLLSCVCHT | LAEYSRQCTH | AGGLPQDWRG | PDFCPQKCPN | NMQYHECRSP | ||||
CADTCSNQEH | SRACEDHCVA | GCFCPEGTVL | DDIGQTGCVP | VSKCACVYNG | ||||
AAYAPGATYS | TDCTNCTCSG | GRWSCQEVPC | PGTCSVLGGA | HFSTFDGKQY | ||||
TVHGDCSYVL | TKPCDSSAFT | VLAELRRCGL | TDSETCLKSV | TLSLDGAQTV | ||||
VVIKASGEVF | LNQIYTQLPI | SAANVTIFRP | STFFIIAQTS | LGLQLNLQLV | ||||
PTMQLFMQLA | PKLRGQTCGL | CGNFNSIQAD | DFRTLSGVVE | ATAAAFFNTF | ||||
KTQAACPNIR | NSFEDPCSLS | VENEKYAQHW | CSQLTDADGP | FGRCHAAVKP | ||||
GTYYSNCMFD | TCNCERSEDC | LCAALSSYVH | ACAAKGVQLG | GWRDGVCTKP | ||||
MTTCPKSMTY | HYHVSTCQPT | CRSLSEGDIT | CSVGFIPVDG | CICPKGTFLD | ||||
DTGKCVQASN | CPCYHRGSMI | PNGESVHDSG | AICTCTHGKL | SCIGGQAPAP | ||||
VCAAPMVFFD | CRNATPGDTG | AGCQKSCHTL | DMTCYSPQCV | PGCVCPDGLV | ||||
ADGEGGCITA | EDCPCVHNEA | SYRAGQTIRV | GCNTCTCDSR | MWRCTDDPCL | ||||
ATCAVYGDGH | YLTFDGQSYS | FNGDCEYTLV | QNHCGGKDST | QDSFRVVTEN | ||||
VPCGTTGTTC | SKAIKIFLGG | FELKLSHGKV | EVIGTDESQE | VPYTIRQMGI | ||||
YLVVDTDIGL | VLLWDKKTSI | FINLSPEFKG | RVCGLCGNFD | DIAVNDFATR | ||||
SRSVVGDVLE | FGNSWKLSPS | CPDALAPKDP | CTANPFRKSW | AQKQCSILHG | ||||
PTFAACHAHV | EPARYYEACV | NDACACDSGG | DCECFCTAVA | AYAQACHEVG | ||||
LCVSWRTPSI | CPLFCDYYNP | EGQCEWHYQP | CGVPCLRTCR | NPRGDCLRDV | ||||
RGLEGCYPKC | PPEAPIFDED | KMQCVATCPT | PPLPPRCHVH | GKSYRPGAVV | ||||
PSDKNCQSCL | CTERGVECTY | KAEACVCTYN | GQRFHPGDVI | YHTTDGTGGC | ||||
ISARCGANGT | IERRVYPCSP | TTPVPPTTFS | FSTPPLVVSS | THTPSNGPSS | ||||
AHTGPPSSAW | PTTAGTSPRT | RLPTASASLP | PVCGEKCLWS | PWMDVSRPGR | ||||
GTDSGDFDTL | ENLRAHGYRV | CESPRSVECR | AEDAPGVPLR | ALGQRVQCSP | ||||
DVGLTCRNRE | QASGLCYNYQ | IRVQCCTPLP | CSTSSSPAQT | TPPTTSKTTE | ||||
TRASGSSAPS | STPGTVSLST | ARTTPAPGTA | TSVKKTFSTP | SPPPVPATST | ||||
SSMSTTAPGT | SVVSSKPTPT | EPSTSSCLQE | LCTWTEWIDG | SYPAPGINGG | ||||
DFDTFQNLRD | EGYTFCESPR | SVQCRAESFP | NTPLADLGQD | VICSHTEGLI | ||||
CLNKNQLPPI | CYNYEIRIQC | CETVNVCRDI | TRLPKTVATT | RPTPHPTGAQ | ||||
TQTTFTTHMP | SASTEQPTAT | SRGGPTATSV | TQGTHTTLVT | RNCHPRCTWT | ||||
KWFDVDFPSP | GPHGGDKETY | NNIIRSGEKI | CRRPEEITRL | QCRAKSHPEV | ||||
SIEHLGQVVQ | CSREEGLVCR | NQDQQGPFKM | CLNYEVRVLC | CETPRGCHMT | ||||
STPGSTSSSP | AQTTPSTTSK | TTETQASGSS | APSSTPGTVS | LSTARTTPAP | ||||
GTATSVKKTF | STPSPPPVPA | TSTSSMSTTA | PGTSVVSSKP | TPTEPSTSSC | ||||
LQELCTWTEW | IDGSYPAPGI | NGGDFDTFQN | LRDEGYTFCE | SPRSVQCRAE | ||||
SFPNTPLADL | GQDVICSHTE | GLICLNKNQL | PPICYNYEIR | IQCCETVNVC | ||||
RDITRPPKTV | ATTRPTPHPT | GAQTQTTFTT | HMPSASTEQP | TATSRGGPTA | ||||
TSVTQGTHTT | PVTRNCHPRC | TWTTWFDVDF | PSPGPHGGDK | ETYNNIIRSG | ||||
EKICRRPEEI | TRLQCRAKSH | PEVSIEHLGQ | VVQCSREEGL | VCRNQDQQGP | ||||
FKMCLNYEVR | VLCCETPKGC | PVTSTPVTAP | STPSGRATSP | TQSTSSWQKS | ||||
RTTTLVTTST | TSTPQTSTTY | AHTTSTTSAP | TARTTSAPTT | RTTSASPAST | ||||
TSGPGNTPSP | VPTTSTISAP | TTSITSAPTT | STTSAPTSST | TSGPGTTPSP | ||||
VPTTSITSAP | TTSTTSAPTT | STTSARTSST | TSATTTSRIS | GPETTPSPVP | ||||
TTSTTSATTT | STTSAPTTST | TSAPTSSTTS | SPQTSTTSAP | TTSTTSGPGT | ||||
TPSPVPTTST | TSAPTTRTTS | APKSSTTSAA | TTSTTSGPET | TPRPVPTTST | ||||
TSSPTTSTTS | APTTSTTSAS | TTSTTSGAGT | TPSPVPTTST | TSAPTTSTTS | ||||
APISSTTSAT | TTSTTSGPGT | TPSPVPTTST | TSAPTTSTTS | GPGTTPSAVP | ||||
TTSITSAPTT | STNSAPISST | TSATTTSRIS | GPETTPSPVP | TASTTSASTT | ||||
STTSGPGTTP | SPVPTTSTIS | VPTTSTTSAS | TTSTTSASTT | STTSGPGTTP | ||||
SPVPTTSTTS | APTTSTTSAP | TTSTISAPTT | STTSATTTST | TSAPTPRRTS | ||||
APTTSTISAS | TTSTTSATTT | STTSATTTST | ISAPTTSTTL | SPTTSTTSTT | ||||
ITSTTSAPIS | STTSTPQTST | TSAPTTSTTS | GPGTTSSPVP | TTSTTSAPTT | ||||
STTSAPTTRT | TSVPTSSTTS | TATTSTTSGP | GTTPSPVPTT | STTSAPTTRT | ||||
TSAPTTSTTS | APTTSTTSAP | TSSTTSATTT | STISVPTTST | TSVPGTTPSP | ||||
VPTTSTISVP | TTSTTSASTT | STTSGPGTTP | SPVPTTSTTS | APTTSTTSAP | ||||
TTSTISAPTT | STPSAPTTST | TLAPTTSTTS | APTTSTTSTP | TSSTTSSPQT | ||||
STTSASTTSI | TSGPGTTPSP | VPTTSTTSAP | TTSTTSAATT | STISAPTTST | ||||
TSAPTTSTTS | ASTASKTSGL | GTTPSPIPTT | STTSPPTTST | TSASTASKTS | ||||
GPGTTPSPVP | TTSTIFAPRT | STTSASTTST | TPGPGTTPSP | VPTTSTASVS | ||||
KTSTSHVSIS | KTTHSQPVTR | DCHLRCTWTK | WFDIDFPSPG | PHGGDKETYN | ||||
NIIRSGEKIC | RRPEEITRLQ | CRAESHPEVS | IEHLGQVVQC | SREEGLVCRN | ||||
QDQQGPFKMC | LNYEVRVLCC | ETPKGCPVTS | TPVTAPSTPS | GRATSPTQST | ||||
SSWQKSRTTT | LVTTSTTSTP | QTSTTSAPTT | STTSAPTTST | TSAPTTSTTS | ||||
TPQTSISSAP | TSSTTSAPTS | STISARTTSI | ISAPTTSTTS | SPTTSTTSAT | ||||
TTSTTSAPTS | STTSTPQTSK | TSAATSSTTS | GSGTTPSPVT | TTSTASVSKT | ||||
STSHVSVSKT | THSQPVTRDC | HPRCTWTKWF | DVDFPSPGPH | GGDKETYNNI | ||||
IRSGEKICRR | PEEITRLQCR | AKSHPEVSIE | HLGQVVQCSR | EEGLVCRNQD | ||||
QQGPFKMCLN | YEVRVLCCET | PKGCPVTSTS | VTAPSTPSGR | ATSPTQSTSS | ||||
WQKSRTTTLV | TSSITSTTQT | STTSAPTTST | TPASIPSTTS | APTTSTTSAP | ||||
TTSTTSAPTT | STTSTPQTTT | SSAPTSSTTS | APTTSTISAP | TTSTISAPTT | ||||
STTSAPTAST | TSAPTSTSSA | PTTNTTSAPT | TSTTSAPITS | TISAPTTSTT | ||||
STPQTSTISS | PTTSTTSTPQ | TSTTSSPTTS | TTSAPTTSTT | SAPTTSTTST | ||||
PQTSISSAPT | SSTTSAPTAS | TISAPTTSTT | SFHTTSTTSP | PTSSTSSTPQ | ||||
TSKTSAATSS | TTSGSGTTPS | PVPTTSTASV | SKTSTSHVSV | SKTTHSQPVT | ||||
RDCHPRCTWT | KWFDVDFPSP | GPHGGDKETY | NNIIRSGEKI | CRRPEEITRL | ||||
QCRAESHPEV | SIEHLGQVVQ | CSREEGLVCR | NQDQQGPFKM | CLNYEVRVLC | ||||
CETPKGCPVT | STPVTAPSTP | SGRATSPTQS | TSSWQKSRTT | TLVTTSTTST | ||||
PQTSTTSAPT | TSTIPASTPS | TTSAPTTSTT | SAPTTSTTSA | PTHRTTSGPT | ||||
TSTTLAPTTS | TTSAPTTSTN | SAPTTSTISA | STTSTISAPT | TSTISSPTSS | ||||
TTSTPQTSKT | SAATSSTTSG | SGTTPSPVPT | TSTTSASTTS | TTSAPTTSTT | ||||
SGPGTTPSPV | PSTSTTSAAT | TSTTSAPTTR | TTSAPTSSMT | SGPGTTPSPV | ||||
PTTSTTSAPT | TSTTSGPGTT | PSPVPTTSTT | SAPITSTTSG | PGSTPSPVPT | ||||
TSTTSAPTTS | TTSASTASTT | SGPGTTPSPV | PTTSTTSAPT | TRTTSASTAS | ||||
TTSGPGSTPS | PVPTTSTTSA | PTTRTTPAST | ASTTSGPGTT | PSPVPTTSTT | ||||
SASTTSTISL | PTTSTTSAPI | TSMTSGPGTT | PSPVPTTSTT | SAPTTSTTSA | ||||
STASTTSGPG | TTPSPVPTTS | TTSAPTTSTT | SASTASTTSG | PGTSLSPVPT | ||||
TSTTSAPTTS | TTSGPGTTPS | PVPTTSTTSA | PTTSTTSGPG | TTPSPVPTTS | ||||
TTPVSKTSTS | HLSVSKTTHS | QPVTSDCHPL | CAWTKWFDVD | FPSPGPHGGD | ||||
KETYNNIIRS | GEKICRRPEE | ITRLQCRAES | HPEVNIEHLG | QVVQCSREEG | ||||
LVCRNQDQQG | PFKMCLNYEV | RVLCCETPRG | CPVTSVTPYG | TSPTNALYPS | ||||
LSTSMVSASV | ASTSVASSSV | ASSSVAYSTQ | TCFCNVADRL | YPAGSTIYRH | ||||
RDLAGHCYYA | LCSQDCQVVR | GVDSDCPSTT | LPPAPATSPS | ISTSEPVTEL | ||||
GCPNAVPPRK | KGETWATPNC | SEATCEGNNV | ISLRPRTCPR | VEKPTCANGY | ||||
PAVKVADQDG | CCHHYQCQCV | CSGWGDPHYI | TFDGTYYTFL | DNCTYVLVQQ | ||||
IVPVYGHFRV | LVDNYFCGAE | DGLSCPRSII | LEYHQDRVVL | TRKPVHGVMT | ||||
NEIIFNNKVV | SPGFRKNGIV | VSRIGVKMYA | TIPELGVQVM | FSGLIFSVEV | ||||
PFSKFANNTE | GQCGTCTNDR | KDECRTPRGT | VVASCSEMSG | LWNVSIPDQP | ||||
ACHRPHPTPT | TVGPTTVGST | TVGPTTVGST | TVGPTTPPAP | CLPSPICQLI | ||||
LSKVFEPCHT | VIPPLLFYEG | CVFDRCHMTD | LDVVCSSLEL | YAALCASHDI | ||||
CIDWRGRTGH | MCPFTCPADK | VYQPCGPSNP | SYCYGNDSAS | LGALPEAGPI | ||||
TEGCFCPEGM | TLFSTSAQVC | VPTGCPRCLG | PHGEPVKVGH | TVGMDCQECT | ||||
CEAATWTLTC | RPKLCPLPPA | CPLPGFVPVP | AAPQAGQCCP | QYSCACNTSR | ||||
CPAPVGCPEG | ARAIPTYQEG | ACCPVQNCSW | TVCSINGTLY | QPGAVVSSSL | ||||
CETCRCELPG | GPPSDAFVVS | CETQICNTHC | PVGFEYQEQS | GQCCGTCVQV | ||||
ACVTNTSKSP | AHLFYPGETW | SDAGNHCVTH | QCEKHQDGLV | VVTTKKACPP | ||||
LSCSLDEARM | SKDGCCRFCP | PPPPPYQNQS | TCAVYHRSLI | IQQQGCSSSE | ||||
PVRLAYCRGN | CGDSSSMYSL | EGNTVEHRCQ | CCQELRTSLR | NVTLHCTDGS | ||||
SRAFSYTEVE | ECGCMGRRCP | APGDTQHSEE | AEPEPSQEAE | SGSWERGVPV | ||||
SPMH |
Секретований назовні.
Література
- Escande F., Aubert J.-P., Porchet N., Buisine M.P. (2001). Human mucin gene MUC5AC: organization of its 5'-region and central repetitive region. Biochem. J. 358: 763—772. PMID 11535137 DOI:10.1042/0264-6021:3580763
- Li D., Gallup M., Fan N., Szymkowski D.E., Basbaum C.B. (1998). Cloning of the amino-terminal and 5'-flanking region of the human MUC5AC mucin gene and transcriptional up-regulation by bacterial exoproducts. J. Biol. Chem. 273: 6812—6820. PMID 9506983 DOI:10.1074/jbc.273.12.6812
- Klomp L.W., Van Rens L., Strous G.J. (1995). Cloning and analysis of human gastric mucin cDNA reveals two types of conserved cysteine-rich domains. Biochem. J. 308: 831—838. PMID 8948439 DOI:10.1042/bj3080831
- Lidell M.E., Hansson G.C. (2006). Cleavage in the GDPH sequence of the C-terminal cysteine-rich part of the human MUC5AC mucin. Biochem. J. 399: 121—129. PMID 16787389 DOI:10.1042/BJ20060443
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 14: 2121—2127. 2004. PMID 15489334 DOI:10.1101/gr.2596504
- Perez-Vilar J., Randell S.H., Boucher R.C. (2004). C-Mannosylation of MUC5AC and MUC5B Cys subdomains. Glycobiology. 14: 325—337. PMID 14718370 DOI:10.1093/glycob/cwh041
Примітки
- Human PubMed Reference:.
- Mouse PubMed Reference:.
- (англ.) . Архів оригіналу за 13 серпня 2017. Процитовано 8 вересня 2017.
- (англ.) . Архів оригіналу за 24 вересня 2017. Процитовано 8 вересня 2017.
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MUC5AC angl Mucin 5AC oligomeric mucus gel forming bilok yakij koduyetsya odnojmennim genom roztashovanim u lyudej na korotkomu plechi 11 yi hromosomi Dovzhina polipeptidnogo lancyuga bilka stanovit 5 654 aminokislot a molekulyarna masa 585 570 MUC5ACNayavni strukturiPDBPoshuk dlya lyudej PDBe RCSB Spisok kodiv PDB5AJN 5AJP 5AJOIdentifikatoriSimvoliMUC5AC MUC5 TBM leB mucin mucin 5AC oligomeric mucus gel formingZovnishni ID OMIM 158373 MGI 104697 HomoloGene 137237 GeneCards MUC5ACOntologiya genaMolekulyarna funkciya extracellular matrix structural constituentKlitinna komponenta citoplazma Golgi lumen extracellular region ekzosoma mizhklitinnij prostir klitinna membrana mucus layerBiologichnij proces phosphatidylinositol mediated signaling O glycan processing stimulatory C type lectin receptor signaling pathwayDzherela Amigo QuickGOOrtologiVidi Lyudina MishaEntrez4586 17833Ensembl ENSG00000215182 ENSG00000283158 ENSMUSG00000037974UniProt P98088 n dRefSeq mRNK NM 017511 NM 001304359NM 010844RefSeq bilok NP 001291288n dLokus UCSC Hr 11 1 16 1 2 MbHr 7 141 34 141 37 MbPubMed searchVikidaniDiv Red dlya lyudejDiv Red dlya mishej Poslidovnist aminokislot1020304050 MSVGRRKLALLWALALALACTRHTGHAQDGSSESSYKHHPALSPIARGPS GVPLRGATVFPSLRTIPVVRASNPAHNGRVCSTWGSFHYKTFDGDVFRFP GLCNYVFSEHCGAAYEDFNIQLRRSQESAAPTLSRVLMKVDGVVIQLTKG SVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSLLLELD TKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKMDDPTDQCQD PVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCED TDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSP CADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNG AAYAPGATYSTDCTNCTCSGGRWSCQEVPCPGTCSVLGGAHFSTFDGKQY TVHGDCSYVLTKPCDSSAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTV VVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLV PTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTF KTQAACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKP GTYYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKP MTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLD DTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCTHGKLSCIGGQAPAP VCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVCPDGLV ADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCL ATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTEN VPCGTTGTTCSKAIKIFLGGFELKLSHGKVEVIGTDESQEVPYTIRQMGI YLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATR SRSVVGDVLEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHG PTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVG LCVSWRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCLRDV RGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRPGAVV PSDKNCQSCLCTERGVECTYKAEACVCTYNGQRFHPGDVIYHTTDGTGGC ISARCGANGTIERRVYPCSPTTPVPPTTFSFSTPPLVVSSTHTPSNGPSS AHTGPPSSAWPTTAGTSPRTRLPTASASLPPVCGEKCLWSPWMDVSRPGR GTDSGDFDTLENLRAHGYRVCESPRSVECRAEDAPGVPLRALGQRVQCSP DVGLTCRNREQASGLCYNYQIRVQCCTPLPCSTSSSPAQTTPPTTSKTTE TRASGSSAPSSTPGTVSLSTARTTPAPGTATSVKKTFSTPSPPPVPATST SSMSTTAPGTSVVSSKPTPTEPSTSSCLQELCTWTEWIDGSYPAPGINGG DFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICSHTEGLI CLNKNQLPPICYNYEIRIQCCETVNVCRDITRLPKTVATTRPTPHPTGAQ TQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTLVTRNCHPRCTWT KWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEV SIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCHMT STPGSTSSSPAQTTPSTTSKTTETQASGSSAPSSTPGTVSLSTARTTPAP GTATSVKKTFSTPSPPPVPATSTSSMSTTAPGTSVVSSKPTPTEPSTSSC LQELCTWTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAE SFPNTPLADLGQDVICSHTEGLICLNKNQLPPICYNYEIRIQCCETVNVC RDITRPPKTVATTRPTPHPTGAQTQTTFTTHMPSASTEQPTATSRGGPTA TSVTQGTHTTPVTRNCHPRCTWTTWFDVDFPSPGPHGGDKETYNNIIRSG EKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLVCRNQDQQGP FKMCLNYEVRVLCCETPKGCPVTSTPVTAPSTPSGRATSPTQSTSSWQKS RTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPAST TSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSAPTSSTTSGPGTTPSP VPTTSITSAPTTSTTSAPTTSTTSARTSSTTSATTTSRISGPETTPSPVP TTSTTSATTTSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGT TPSPVPTTSTTSAPTTRTTSAPKSSTTSAATTSTTSGPETTPRPVPTTST TSSPTTSTTSAPTTSTTSASTTSTTSGAGTTPSPVPTTSTTSAPTTSTTS APISSTTSATTTSTTSGPGTTPSPVPTTSTTSAPTTSTTSGPGTTPSAVP TTSITSAPTTSTNSAPISSTTSATTTSRISGPETTPSPVPTASTTSASTT STTSGPGTTPSPVPTTSTISVPTTSTTSASTTSTTSASTTSTTSGPGTTP SPVPTTSTTSAPTTSTTSAPTTSTISAPTTSTTSATTTSTTSAPTPRRTS APTTSTISASTTSTTSATTTSTTSATTTSTISAPTTSTTLSPTTSTTSTT ITSTTSAPISSTTSTPQTSTTSAPTTSTTSGPGTTSSPVPTTSTTSAPTT STTSAPTTRTTSVPTSSTTSTATTSTTSGPGTTPSPVPTTSTTSAPTTRT TSAPTTSTTSAPTTSTTSAPTSSTTSATTTSTISVPTTSTTSVPGTTPSP VPTTSTISVPTTSTTSASTTSTTSGPGTTPSPVPTTSTTSAPTTSTTSAP TTSTISAPTTSTPSAPTTSTTLAPTTSTTSAPTTSTTSTPTSSTTSSPQT STTSASTTSITSGPGTTPSPVPTTSTTSAPTTSTTSAATTSTISAPTTST TSAPTTSTTSASTASKTSGLGTTPSPIPTTSTTSPPTTSTTSASTASKTS GPGTTPSPVPTTSTIFAPRTSTTSASTTSTTPGPGTTPSPVPTTSTASVS KTSTSHVSISKTTHSQPVTRDCHLRCTWTKWFDIDFPSPGPHGGDKETYN NIIRSGEKICRRPEEITRLQCRAESHPEVSIEHLGQVVQCSREEGLVCRN QDQQGPFKMCLNYEVRVLCCETPKGCPVTSTPVTAPSTPSGRATSPTQST SSWQKSRTTTLVTTSTTSTPQTSTTSAPTTSTTSAPTTSTTSAPTTSTTS TPQTSISSAPTSSTTSAPTSSTISARTTSIISAPTTSTTSSPTTSTTSAT TTSTTSAPTSSTTSTPQTSKTSAATSSTTSGSGTTPSPVTTTSTASVSKT STSHVSVSKTTHSQPVTRDCHPRCTWTKWFDVDFPSPGPHGGDKETYNNI IRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLVCRNQD QQGPFKMCLNYEVRVLCCETPKGCPVTSTSVTAPSTPSGRATSPTQSTSS WQKSRTTTLVTSSITSTTQTSTTSAPTTSTTPASIPSTTSAPTTSTTSAP TTSTTSAPTTSTTSTPQTTTSSAPTSSTTSAPTTSTISAPTTSTISAPTT STTSAPTASTTSAPTSTSSAPTTNTTSAPTTSTTSAPITSTISAPTTSTT STPQTSTISSPTTSTTSTPQTSTTSSPTTSTTSAPTTSTTSAPTTSTTST PQTSISSAPTSSTTSAPTASTISAPTTSTTSFHTTSTTSPPTSSTSSTPQ TSKTSAATSSTTSGSGTTPSPVPTTSTASVSKTSTSHVSVSKTTHSQPVT RDCHPRCTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRL QCRAESHPEVSIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLC CETPKGCPVTSTPVTAPSTPSGRATSPTQSTSSWQKSRTTTLVTTSTTST PQTSTTSAPTTSTIPASTPSTTSAPTTSTTSAPTTSTTSAPTHRTTSGPT TSTTLAPTTSTTSAPTTSTNSAPTTSTISASTTSTISAPTTSTISSPTSS TTSTPQTSKTSAATSSTTSGSGTTPSPVPTTSTTSASTTSTTSAPTTSTT SGPGTTPSPVPSTSTTSAATTSTTSAPTTRTTSAPTSSMTSGPGTTPSPV PTTSTTSAPTTSTTSGPGTTPSPVPTTSTTSAPITSTTSGPGSTPSPVPT TSTTSAPTTSTTSASTASTTSGPGTTPSPVPTTSTTSAPTTRTTSASTAS TTSGPGSTPSPVPTTSTTSAPTTRTTPASTASTTSGPGTTPSPVPTTSTT SASTTSTISLPTTSTTSAPITSMTSGPGTTPSPVPTTSTTSAPTTSTTSA STASTTSGPGTTPSPVPTTSTTSAPTTSTTSASTASTTSGPGTSLSPVPT TSTTSAPTTSTTSGPGTTPSPVPTTSTTSAPTTSTTSGPGTTPSPVPTTS TTPVSKTSTSHLSVSKTTHSQPVTSDCHPLCAWTKWFDVDFPSPGPHGGD KETYNNIIRSGEKICRRPEEITRLQCRAESHPEVNIEHLGQVVQCSREEG LVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSVTPYGTSPTNALYPS LSTSMVSASVASTSVASSSVASSSVAYSTQTCFCNVADRLYPAGSTIYRH RDLAGHCYYALCSQDCQVVRGVDSDCPSTTLPPAPATSPSISTSEPVTEL GCPNAVPPRKKGETWATPNCSEATCEGNNVISLRPRTCPRVEKPTCANGY PAVKVADQDGCCHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQ IVPVYGHFRVLVDNYFCGAEDGLSCPRSIILEYHQDRVVLTRKPVHGVMT NEIIFNNKVVSPGFRKNGIVVSRIGVKMYATIPELGVQVMFSGLIFSVEV PFSKFANNTEGQCGTCTNDRKDECRTPRGTVVASCSEMSGLWNVSIPDQP ACHRPHPTPTTVGPTTVGSTTVGPTTVGSTTVGPTTPPAPCLPSPICQLI LSKVFEPCHTVIPPLLFYEGCVFDRCHMTDLDVVCSSLELYAALCASHDI CIDWRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPI TEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQECT CEAATWTLTCRPKLCPLPPACPLPGFVPVPAAPQAGQCCPQYSCACNTSR CPAPVGCPEGARAIPTYQEGACCPVQNCSWTVCSINGTLYQPGAVVSSSL CETCRCELPGGPPSDAFVVSCETQICNTHCPVGFEYQEQSGQCCGTCVQV ACVTNTSKSPAHLFYPGETWSDAGNHCVTHQCEKHQDGLVVVTTKKACPP LSCSLDEARMSKDGCCRFCPPPPPPYQNQSTCAVYHRSLIIQQQGCSSSE PVRLAYCRGNCGDSSSMYSLEGNTVEHRCQCCQELRTSLRNVTLHCTDGS SRAFSYTEVEECGCMGRRCPAPGDTQHSEEAEPEPSQEAESGSWERGVPV SPMH A Alanin C Cisteyin D Asparaginova kislota E Glutaminova kislota F Fenilalanin G Glicin H Gistidin I Izolejcin K Lizin L Lejcin M Metionin N Asparagin P Prolin Q Glutamin R Arginin S Serin T Treonin V Valin W Triptofan Y Tirozin Sekretovanij nazovni LiteraturaEscande F Aubert J P Porchet N Buisine M P 2001 Human mucin gene MUC5AC organization of its 5 region and central repetitive region Biochem J 358 763 772 PMID 11535137 DOI 10 1042 0264 6021 3580763 Li D Gallup M Fan N Szymkowski D E Basbaum C B 1998 Cloning of the amino terminal and 5 flanking region of the human MUC5AC mucin gene and transcriptional up regulation by bacterial exoproducts J Biol Chem 273 6812 6820 PMID 9506983 DOI 10 1074 jbc 273 12 6812 Klomp L W Van Rens L Strous G J 1995 Cloning and analysis of human gastric mucin cDNA reveals two types of conserved cysteine rich domains Biochem J 308 831 838 PMID 8948439 DOI 10 1042 bj3080831 Lidell M E Hansson G C 2006 Cleavage in the GDPH sequence of the C terminal cysteine rich part of the human MUC5AC mucin Biochem J 399 121 129 PMID 16787389 DOI 10 1042 BJ20060443 The status quality and expansion of the NIH full length cDNA project the Mammalian Gene Collection MGC Genome Res 14 2121 2127 2004 PMID 15489334 DOI 10 1101 gr 2596504 Perez Vilar J Randell S H Boucher R C 2004 C Mannosylation of MUC5AC and MUC5B Cys subdomains Glycobiology 14 325 337 PMID 14718370 DOI 10 1093 glycob cwh041PrimitkiHuman PubMed Reference Mouse PubMed Reference angl Arhiv originalu za 13 serpnya 2017 Procitovano 8 veresnya 2017 angl Arhiv originalu za 24 veresnya 2017 Procitovano 8 veresnya 2017 Div takozhHromosoma 11 Ce nezavershena stattya pro bilki Vi mozhete dopomogti proyektu vipravivshi abo dopisavshi yiyi